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αvβ3-integrin-targeting-DPPC-cholesterol nanoliposome

Based on

1 Articles
2015 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

1,2-dipalmitoyl-sn-glycero-phosphatidylcholine

dipalmitoyl phosphatidylcholine dipalmitoylphosphatidylcholine DPPC
Type Single Compound
Formula C40H80NO8P
Role layer
3

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material
4

αvβ3-integrin targeting peptide

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
4T1 breast cancer metastases bearing BALB/c mice

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • DSPE-PEG-αvβ3-integrin targeting peptide
  • 1,2-dipalmitoyl-sn-glycero-phosphatidylcholine
  • phosphate buffer solution
  1. 3DsF02Q
  2. iwncUJJ
Product

αvβ3-integrin-targeting-DPPC-cholesterol nanoliposome

Hydrodynamic diameter: 100.9 - 107.1 nm

Size: ~ 100 nm

Medium/Support: none

References

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