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docetaxel, wortmannin-loaded poly(ethylene glycol)-co-poly(lactic-co-glycolic acid) diblock copolymer nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

poly(ethylene glycol)-co-poly(lactic-co-glycolic acid) diblock copolymer

PEG-PLGA
Type Polymer
Formula
Role raw materials
2

poly(ethylene glycol)-co-poly(lactic-co-glycolic acid) diblock copolymer

PEG-PLGA
Type Polymer
Formula
Role raw materials
3

wortmannin

wotrmannin Wtmn
Type Single Compound
Formula C23H24O8
Role loaded material
4

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role loaded material

Properties

Applications

Area Application Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Source
healthy tumor-free CD1 mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • wortmannin
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • poly(ethylene glycol)-co-poly(lactic-co-glycolic acid) diblock copolymer
  1. 9Vb37wyVoQGfdxXMvRn1SusT
  2. J0HMl9
Product

docetaxel, wortmannin-loaded poly(ethylene glycol)-co-poly(lactic-co-glycolic acid) diblock copolymer nanoparticles

References

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