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doxorubicin-loaded-IGF1-modified-amphiphilic polymer-coated-iron oxide nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

iron oxide

Type Single Compound
Formula FeO(x)
Role core
2

amphiphilic polymer

Type Polymer
Formula
Role layer
3

IGF1 receptor

Type Biomolecule
Formula
Role layer
4

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
MIAPaCa-2 human pancreatic cancer cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Product

doxorubicin-loaded-IGF1-modified-amphiphilic polymer-coated-iron oxide nanoparticles

Core size: 10 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

doxorubicin-loaded-IGF1-modified-amphiphilic polymer-coated-iron oxide nanoparticles

Core size: 10 nm

Hydrodynamic diameter: ~ 80 nm

Medium: Dulbecco's modified Eagle medium

Support: none

Method 3

Type: Physical formation
Source:
  1. ZP7dTlGxxyZMh
Product

doxorubicin-loaded-IGF1-modified-amphiphilic polymer-coated-iron oxide nanoparticles

Core size: 10 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Product

doxorubicin-loaded-IGF1-modified-amphiphilic polymer-coated-iron oxide nanoparticles

Core size: 10 nm

Hydrodynamic diameter: ~ 20 nm

Medium: phosphate buffer solution

Support: none

References

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