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CPP-functionalized multidrug-loaded acetylated dextran-coated porous silicon nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

porous silicon nanoparticles

PSi NP
Type Nano Material
Formula
Role core
2

acetylated dextran

AcDX
Type Biomolecule
Formula
Role layer
3

cell-penetrating peptide

CPP
Type Biomolecule
Formula
Role layer
4

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide

sorafenib SFN SOR SF
Type Single Compound
Formula C21H16ClF3N4O3
Role loaded material
5

Paclitaxel

Plaxicel Abraxane Paxene Taxol PCL PAC PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
MCF-7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

CPP-functionalized multidrug-loaded acetylated dextran-coated porous silicon nanoparticles

Hydrodynamic diameter: ~ 400 nm

Medium: water

Support: none

Method 2

Type: Chemical synthesis
Source:
Product

CPP-functionalized multidrug-loaded acetylated dextran-coated porous silicon nanoparticles

Size: not specified

Medium/Support: none

References

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