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siRNA-encapsulated-MC3:DSPC:Chol:DMG-PEG:DSPE-PEG-Mal-lipid based nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

small interfering RNA

RNA molecule
Type Biomolecule
Formula
Role core
2

MC3:DSPC:Chol:DMG-PEG:DSPE-PEG-Mal mixture

lipid mixture
Type Complex Compound
Formula
Role layer
3

CD4 IgG monoclonal antibody

Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
C57BL/6 mice

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Preparation

Method 1

Type: Chemical synthesis
Source:
Product

siRNA-encapsulated-MC3:DSPC:Chol:DMG-PEG:DSPE-PEG-Mal-lipid based nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • MC3:DSPC:Chol:DMG-PEG:DSPE-PEG-Mal mixture
  • water
  • small interfering RNA
  1. jWoUU6g
  2. GKtMj6zKBnH67EjwphvRPoK
Product

siRNA-encapsulated-MC3:DSPC:Chol:DMG-PEG:DSPE-PEG-Mal-lipid based nanoparticles

Hydrodynamic diameter: 124 - 134 nm

Medium: water

Support: none

Method 3

Type: Chemical synthesis
Source:
  1. 5JF1
Product

siRNA-encapsulated-MC3:DSPC:Chol:DMG-PEG:DSPE-PEG-Mal-lipid based nanoparticles

Size: not specified

Medium/Support: none

References

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