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Tween 80-stabilized-AM-005-loaded-oleic acid-capped-Fe3O4 nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

oleic acid-capped-Fe3O4 nanoparticles

Type Nano Material
Formula
Role core
2

6-chloro-2-(methylsulfanyl)-N-(3-{5-[(piperidin-1-yl)methyl]-1H-1,3-benzodiazol-2-yl}-1H-pyrazol-4-yl)pyrimidin-4-amine

aurora kinase inhibitor AM-005
Type Single Compound
Formula C21H23ClN8S
Role loaded material
3

polyoxyethylene (20) sorbitan monooleate

Polysorbate 80 Alkest TW 80 Tween 80
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
HepG2 human liver cancer cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. Ccj
  2. eOY7CWd
Product

Tween 80-stabilized-AM-005-loaded-oleic acid-capped-Fe3O4 nanoparticles

Diameter: 9.25 - 14.14 nm

Hydrodynamic diameter: 78.9 - 80.1 nm

Medium/Support: none

References

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