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FR-targeting PTX nanoplatforms

Based on

1 Articles
2015 Most recent source

Composition

1

sucrose-HEPES-saline buffer

Type Complex Compound
Formula
Role core
2

paclitaxel-GFLG-PAMAM dendrimer conjugate

PGD conjugate
Type Polymer
Formula
Role loaded material
3

egg phosphatidylcholine

ePC
Type Complex Compound
Formula
Role layer
4

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material
5

PEG-DSPE

Type Polymer
Formula
Role loaded material
6

folate-bound poly(ethylene glycol)-distearoylphosphatidylethanolamine

FA-PEG-DSPE
Type Polymer
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human breast cancer BT-20 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

FR-targeting PTX nanoplatforms

Hydrodynamic diameter: 206.86 - 217.14 nm

Medium: sucrose-HEPES-saline buffer

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • PEG-DSPE
  • cholesterol
  • paclitaxel-GFLG-PAMAM dendrimer conjugate
See all (5)
  1. b8cGRLalWgUE4V5yn0DbkvGlS2lv5crZCh8
  2. rQf3aA4FjDLxAANbkZT6hS
Product

FR-targeting PTX nanoplatforms

Diameter: 190 - 220 nm

Medium/Support: none

References

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