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holo-transferrin-conjugated siRNA LOR-1284-loaded 1,2-dioleyloxy-N,N-dimethyl-3-aminopropane/egg phosphatidylcholine/methoxypolyethylene glycol - distearoyl phosphatidylethanolamine nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

HEPES buffered saline

HEPES
Type Complex Compound
Formula
Role core
2

1,2-dioleyloxy-N,N-dimethyl-3-aminopropane/egg phosphatidylcholine/methoxypolyethylene glycol - distearoyl phosphatidylethanolamine

DODMA/EggPC/mPEg-DSPE
Type Complex Compound
Formula
Role layer
3

LOR-1284 siRNA

Type Biomolecule
Formula
Role loaded material
4

holo-transferrin-terminated poly(ethylene glycol)-distearoyl phosphatidylethanolamine

holo-Tf-PEG-DSPE
Type Complex Compound
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Source
stability in serum

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Applications

Area Application Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Source
ICR mouse

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • egg phosphatidylcholine
  • 1,2-dioleyloxy-N,N-dimethyl-3-aminopropane
  • methoxypolyethylene glycol - distearoyl phosphatidylethanolamine
  1. deU2a1BDg9wliYJyBA
Product

holo-transferrin-conjugated siRNA LOR-1284-loaded 1,2-dioleyloxy-N,N-dimethyl-3-aminopropane/egg phosphatidylcholine/methoxypolyethylene glycol - distearoyl phosphatidylethanolamine nanoparticles

References

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