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D4 peptide-conjugated fluorescein isothiocyanate isomer I-labeled APTES-functionalized PEGylated silica nanoparticles aqueous suspension

Based on

1 Articles
2014 Most recent source

Composition

1

silicon dioxide

silicic oxide silica
Type Single Compound
Formula SiO2
Role core
2

fluorescein-5-isothiocyanate-3-aminopropyltriethoxysilane moiety

fluorescein isothiocyanate-3-aminopropyltrimethoxysilane moiety fluorescein isothiocyanate-3-aminopropyltriethoxysilane moiety fluorescein isothiocyanate/3-aminopropyltriethoxysilane moiety N-1-(3-trimethoxysilylpropyl)-N'-fluorescyl thiourea moiety fluorescein isothiocyanate-3-aminopropyltrioxysilane moiety APTMS-FITC conjugate moiety FITC-APTES conjugate moiety FITC-APTES moiety FITC-APTMS moiety FITS/APTES moiety FITC-APTS moiety FITC-APS moiety
Type Single Compound
Formula -C24H19N2O8SSi-
Role layer
3

(3-aminopropyl)trimethoxysilane moiety

(3-aminopropyl)trimethoxysilane moiety (3-aminopropyl)triethoxysilane moiety γ-aminopropyltriethoxy silane moiety 3-aminopropyltrimethoxysilane moiety γ-aminopropyltriethoxysilane moiety 3-aminopropyltriethoxysilane moiety (3-aminopropyl)trioxysilane moiety (3-aminopropyl)silanetrioxy group 3-aminopropylsilanetrioxy group 3-aminopropylsiloxy fragment 3-aminopropyl silane moiety 3-aminopropylsilane moiety γ-APTES moiety 3-APTS moiety APTES moiety APTMS moiety AMPS moiety APTS moiety APS moiety
Type Single Compound
Formula -C3H8NO3Si-
Role layer
4

succinimidyl ([N-maleimidoproprionamido]-octylethyleneglycol) ester moiety

SM(PEG)8 moiety
Type Single Compound
Formula -C25H41N2O12
Role layer
5

N-succinimidyl-S-acetyl(thiotetraethylene glycol) moiety

SAT(PEG)4 moiety
Type Single Compound
Formula -C11H20O5S-
Role layer
6

D4 peptide

Type Biomolecule
Formula
Role layer

Properties

Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
cancer MDA-MB-435S cells transfected with Neg1

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • D4 peptide
  • N-succinimidyl S-acetyl (thiotetraethyleneglycol) ester
  1. UeDl
  2. VVf
  3. x2Bw3q
Product

D4 peptide-conjugated fluorescein isothiocyanate isomer I-labeled APTES-functionalized PEGylated silica nanoparticles aqueous suspension

Diameter: 63 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • D4 peptide
  • N-succinimidyl S-acetyl (thiotetraethyleneglycol) ester
  1. NM3F
  2. 5aC
  3. vjuVUB
Product

D4 peptide-conjugated fluorescein isothiocyanate isomer I-labeled APTES-functionalized PEGylated silica nanoparticles aqueous suspension

Hydrodynamic diameter: 89 nm

Medium: water

Support: none

References

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