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1,2-dioleoyl-3-trimethylammonium-propane:1,2-dioleoyl-sn-glycero-3-phosphocholine:3β-[N-(N',N'-dimethylaminoethane)carbamoyl]cholesterol:dioleoylphosphatidylethanolamine:dioleoylphosphatidylethanolamine-polyethylene glycol liposome-plasma proteins complexes

Based on

1 Articles
2014 Most recent source

Composition

1

aqueous Tris-HCl buffer

Type Complex Compound
Formula
Role core
2

1,2-dioleoyl-3-trimethylammonium-propane:1,2-dioleoyl-sn-glycero-3-phosphocholine:3β-[N-(N',N'-dimethylaminoethane)carbamoyl]cholesterol:dioleoylphosphatidylethanolamine:dioleoylphosphatidylethanolamine-polyethylene glycol

DOTAP:DOPC:DC-Chol:DOPE:DOPE-PEG
Type Complex Compound
Formula
Role layer
3

plasma proteins

Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Source
colloidal stability

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Applications

Area Application Source
drug delivery

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Characterization

Method Source
dynamic light scattering dependent on aging time

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Biological effects

Biological system Test details Source
PC3 prostate carcinoma cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,2-dioleoyl-3-trimethylammonium-propane:1,2-dioleoyl-sn-glycero-3-phosphocholine:3β-[N-(N',N'-dimethylaminoethane)carbamoyl]cholesterol:dioleoylphosphatidylethanolamine:dioleoylphosphatidylethanolamine-polyethylene glycol
  • aqueous Tris-HCl buffer
Product

1,2-dioleoyl-3-trimethylammonium-propane:1,2-dioleoyl-sn-glycero-3-phosphocholine:3β-[N-(N',N'-dimethylaminoethane)carbamoyl]cholesterol:dioleoylphosphatidylethanolamine:dioleoylphosphatidylethanolamine-polyethylene glycol liposome-plasma proteins complexes

Method 2

Type: Physical formation
Source:
Starting materials
  • 1,2-dioleoyl-3-trimethylammonium-propane:1,2-dioleoyl-sn-glycero-3-phosphocholine:3β-[N-(N',N'-dimethylaminoethane)carbamoyl]cholesterol:dioleoylphosphatidylethanolamine:dioleoylphosphatidylethanolamine-polyethylene glycol
  • aqueous Tris-HCl buffer
Product

1,2-dioleoyl-3-trimethylammonium-propane:1,2-dioleoyl-sn-glycero-3-phosphocholine:3β-[N-(N',N'-dimethylaminoethane)carbamoyl]cholesterol:dioleoylphosphatidylethanolamine:dioleoylphosphatidylethanolamine-polyethylene glycol liposome-plasma proteins complexes

Method 3

Type: Physical formation
Source:
Starting materials
  • 1,2-dioleoyl-3-trimethylammonium-propane:1,2-dioleoyl-sn-glycero-3-phosphocholine:3β-[N-(N',N'-dimethylaminoethane)carbamoyl]cholesterol:dioleoylphosphatidylethanolamine:dioleoylphosphatidylethanolamine-polyethylene glycol
  • aqueous Tris-HCl buffer
Product

1,2-dioleoyl-3-trimethylammonium-propane:1,2-dioleoyl-sn-glycero-3-phosphocholine:3β-[N-(N',N'-dimethylaminoethane)carbamoyl]cholesterol:dioleoylphosphatidylethanolamine:dioleoylphosphatidylethanolamine-polyethylene glycol liposome-plasma proteins complexes

References

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