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HER2 antibody-conjugated doxorubicin- and hollow gold nanospheres-loaded liposomes

Based on

1 Articles
2015 Most recent source

Composition

1

aqueous solution

Type Complex Compound
Formula
Role core
2

OMP-modified hollow gold nanospheres

OMP-HAuNS
Type Nano Material
Formula
Role loaded material
3

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material
4

1,2-dipalmitoyl-sn-glycero-phosphatidylcholine

dipalmitoyl phosphatidylcholine dipalmitoylphosphatidylcholine DPPC
Type Single Compound
Formula C40H80NO8P
Role layer
5

[(2R)-2,3-di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate

non-deuterated 1,2-distearoyl-sn-glycero-3-phosphocholine 1,2-distearoyl-sn-glycerol-3-phosphatidylcholine 1,2-distearoyl-sn-glycero-3-phosphatidylcholine 1,2-dioctadecanoyl-sn-glycero-3-phosphocholine L-α 1,2-distearoyl-sn-glycero-3-phosphocholine 1,2-distearoyl-sn-glycero-3-phosphorylcholine hydrogenated soy sn-glycero-3-phosphocholine 1,2-dipalmitoyl-sn-glycero-3-phosphocholine 1,2-Distearoyl-sn-glycero-3-phosphocholine 1,2-distearoyl-sn-glycero-3-phosphocholine hydrogenated soy L-α-phosphatidylcholine hydrogenated soybean phosphatidylcholine distearoyl-sn-glycero-3-phosphocholine hydrogenated soya phosphatidylcholine hydrogenated soy phosphatidylcholine Hydrogenated soy phosphatidylcholine hydrogenated L-α-phosphatidylcholine distearyl-L-α-phosphatidylcholine distearoyl phosphatidylcholine distearyl phosphatidyl choline distearoylphosphatidylcholine L-α-phosphatidylcholine egg PC hDSPC DSPC HSPC DSCP
Type Single Compound
Formula C44H88NO8P
Role loaded material
6

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material
7

DSPE-PEG2000-NH2

Type Polymer
Formula
Role loaded material
8

human epidermal growth factor receptor-2 antibody

HER2-antibody HER2ab
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Source
Zeta potential

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Applications

Area Application Source
drug delivery

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
Balb/c mouse with human ovarian carcinoma SKOV3 cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. GGW4oFzx
  2. 9RVM57a
  3. LZCGBBEzIK
Product

HER2 antibody-conjugated doxorubicin- and hollow gold nanospheres-loaded liposomes

Method 2

Type: Physical formation
Source:
Product

HER2 antibody-conjugated doxorubicin- and hollow gold nanospheres-loaded liposomes

References

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