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FTY720-loaded bilamellar nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol

Fingolimod FTY720
Type Single Compound
Formula C19H33NO2
Role loaded material
3

liposomal lipid bilayer

Type Nano Material
Formula
Role layer
4

liposomal lipid bilayer

Type Nano Material
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on media

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
cryo-electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
chronic lymphocytic leukemia (CLL) patient B cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

FTY720-loaded bilamellar nanoparticles

Hydrodynamic diameter: 154.59 - 160.41 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol
  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(methoxypolyethylene glycol)]
See all (4)
  1. 4Zx3E80Y6ekpmjIRNg7
Product

FTY720-loaded bilamellar nanoparticles

Diameter: ~ 70 - 250 nm

Medium/Support: none

References

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