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siRNA-loaded phospholipid-modified polyethylenimine-based nanopreparations

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

DOPE-PEI conjugate

DOPE-PEI
Type Polymer
Formula
Role raw materials
2

siRNA duplex targeting Green Fluorescent Protein

GFP-siRNA
Type Biomolecule
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
stability against enzymatic degradation

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Applications

Area Application Nanomaterial Variant Source
genetic engineering

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
mouse yolk sac embryo c166-GFP cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • siRNA duplex targeting Green Fluorescent Protein
  • DOPE-PEI conjugate
  • buffered HEPES glucose
Product

siRNA-loaded phospholipid-modified polyethylenimine-based nanopreparations

Hydrodynamic diameter: 144 - 212 nm

Medium: buffered HEPES glucose

Support: none

Method 2

Type: Chemical synthesis
Source:
Product

siRNA-loaded phospholipid-modified polyethylenimine-based nanopreparations

Diameter: ~ 100 nm

Medium/Support: none

References

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