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5-FU--loaded EGF-grafted hollow mesoporous SiO2 nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

Vacuous

Type
Formula
Role core
2

silicon dioxide

silicic oxide silica
Type Single Compound
Formula SiO2
Role layer
3

(3-aminopropyl)-triethoxysilane moiety

(3-aminopropyl)trimethoxysilane moiety (3-aminopropyl)triethoxysilane moiety γ-aminopropyltriethoxy silane moiety 3-aminopropyltrimethoxysilane moiety 3-aminopropyltriethoxysilane moiety γ-aminopropyltriethoxysilane moiety (3-aminopropyl)trioxysilane moiety (3-aminopropyl)silanetrioxy group 3-aminopropylsilanetrioxy group 3-aminopropylsiloxy fragment 3-aminopropyl silane moiety 3-aminopropylsilane moiety γ-APTES moiety 3-APTS moiety APTES moiety APTMS moiety AMPS moiety APTS moiety APS moiety
Type Single Compound
Formula -C3H8NO3Si-
Role layer
4

epidermal growth factor

EGF
Type Biomolecule
Formula
Role graft
5

5-fluoro-2,4(1H,3H)pyrimidinedione

5-Fluorouracil 5-fluorouracil fluorouracil Adrucil® Efudex® adrucil efudex 5-FU 5-Fu 5FU
Type Single Compound
Formula C4H3FN2O2
Role loaded material

Properties

Applications

Characterization

Biological effects

Biological system Test details Source
drug resistant human colon adenocarcinoma (SW480/ADR) cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. SZkZpYduZz27b6Ddy
  2. bPfxRDry
Product

5-FU--loaded EGF-grafted hollow mesoporous SiO2 nanoparticles

References

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