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PEG-PLL/siRNA micelles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(ethylene glycol)-block-poly(L-lysine)

mPEG-b-PLLys
Type Polymer
Formula
Role raw materials
2

small interfering RNA

siRNA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c mouse with human pancreatic cancer PANC-1 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(ethylene glycol)-block-poly(L-lysine)
  • scrambled small interfering RNA
  1. WSQk3Sxxae9jr9RJC49F8oYY1LRhP18sLWRnI9b
Product

PEG-PLL/siRNA micelles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

PEG-PLL/siRNA micelles

Hydrodynamic diameter: 60 - 65 nm

Medium: DLS medium

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • poly(ethylene glycol)-block-poly(L-lysine)
  • small interfering RNA
  1. kDK3weGDVCVxEnqwIHmj1afOlEylyOF73fDwL4y
Product

PEG-PLL/siRNA micelles

Diameter: 55 - 70 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • poly(ethylene glycol)-block-poly(L-lysine)
  • mutant Kras small interfering RNA
  1. vokPZUccMSLlKADYJCfR7DCe0biYUlWBx5zYjZx
Product

PEG-PLL/siRNA micelles

Size: not specified

Medium/Support: none

References

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