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iron oxide nanocrystals and paclitaxel-loaded lipid nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

cholesteryl oleate/triolein

Type Complex Compound
Formula
Role core
2

Paclitaxel

Abraxane Plaxicel Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material
3

iron oxide nanocrystals

magnetic nanocrystals Fe3O4 nanocrystals IONC
Type Nano Material
Formula
Role loaded material
4

phosphatidyl glycerol/DOPE/cholesterol

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human breast adenocarcinoma MCF-7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

iron oxide nanocrystals and paclitaxel-loaded lipid nanoparticles

Diameter: ~ 200 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • glycerol trioleate
  • (9Z)-9-octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
  • iron oxide nanocrystals
See all (7)
  1. CWdkROMCeGSq1jfRZTGSA8t
Product

iron oxide nanocrystals and paclitaxel-loaded lipid nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Product

iron oxide nanocrystals and paclitaxel-loaded lipid nanoparticles

Diameter: ~ 209 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
Product

iron oxide nanocrystals and paclitaxel-loaded lipid nanoparticles

Diameter: 122.9 - 150.3 nm

Medium: phosphate buffer solution

Support: none

References

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