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paclitaxel-loaded poly(2-ethylbutoxy phospholane)-block-poly(2-butynyl phospholane)-graft-poly(ethylene glycol) knedel-like nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

hexa(ethylene glycol) dithiol-crosslinked poly(2-ethylbutoxy phospholane)-block-poly(2-butynyl phospholane)-graft-poly(ethylene glycol)

hexa(ethylene glycol) dithiol-crosslinked PEBP-b-PBYP-g-PEG
Type Polymer
Formula
Role raw materials
2

Paclitaxel

Plaxicel Abraxane Paxene Taxol PCL PAC PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
cryo-electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
CCH-OS-O osteosarcoma cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

paclitaxel-loaded poly(2-ethylbutoxy phospholane)-block-poly(2-butynyl phospholane)-graft-poly(ethylene glycol) knedel-like nanoparticles

Diameter: 20 - 28 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
  1. Uw8Su9gOMK5rrnxL8IU
Product

paclitaxel-loaded poly(2-ethylbutoxy phospholane)-block-poly(2-butynyl phospholane)-graft-poly(ethylene glycol) knedel-like nanoparticles

Hydrodynamic diameter: 18 - 30 nm

Medium: water

Support: none

References

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