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doxorubicin/dasatinib-loaded mPEG-lysyl-(a-Fmoc-ε-Cbz-lysine)2 micelles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

mPEG-lysyl-(a-Fmoc-ε-Cbz-lysine)2

PLFCL
Type Polymer
Formula
Role raw materials
2

doxorubicin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material
3

dasatinib

DAS
Type Single Compound
Formula C22H26ClN7O2S
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
4T1.2 mouse metastatic breast cancer cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • dasatinib
  • mPEG-lysyl-(a-Fmoc-ε-Cbz-lysine)2
  • doxorubicin
  1. Gf3
  2. QAEX5MDv
Product

doxorubicin/dasatinib-loaded mPEG-lysyl-(a-Fmoc-ε-Cbz-lysine)2 micelles

Hydrodynamic diameter: 24.6 - 26.2 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • dasatinib
  • mPEG-lysyl-(a-Fmoc-ε-Cbz-lysine)2
  • doxorubicin
  1. p4n
  2. 7TjqJ8Hg
Product

doxorubicin/dasatinib-loaded mPEG-lysyl-(a-Fmoc-ε-Cbz-lysine)2 micelles

Size: not specified

Medium/Support: none

References

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