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LCP-based p-Trp2 vaccine nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

calcium orthophosphate

calcium orthophosphate tricalcium phosphate calcium phosphate β-TCP CaPh TCP CaP CP
Type Single Compound
Formula Ca3(PO4)2
Role core
2

N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecenoyloxy]-1-propanaminium

(N-[1-(2, 3-dioleoyloxy)propyl]-N,N,N-trimethylammoniumsalt) 1,2-di(9Z-octadecenoyloxy)-3-trimethylammonium-propane N-(1-(2,3-dioleoyloxy)propyl)-N,N,N-trimethylammonium N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium 1,2-di-(9Z-octadecenoyl)-3-trimethylammonium-propane 1,2-dioleoyloxy-3-trimethylammonium-propane 1,2-dioleoyl-3-(trimethylammonium)propane 1,2-dioleoyl-3-trimethyl-ammonium-propane 1,2-dioleoyl-3-trimethylammonium propane 1,2-dioleoyl-3-trimethylammonium-propane 1,2-dioleoyl-3-trimethylammonium-propan 1,2-dioleoyl-3-trimethylammoniumpropane DOTAP
Type Single Compound
Formula C42H80NO4
Role layer
3

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material
4

1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) 2000

DSPE-PEG 2000 DSPE-PEG
Type Polymer
Formula
Role loaded material
5

1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol)-mannose

DSPE-PEG-mannose
Type Polymer
Formula
Role loaded material
6

p-Trp2 peptide

p-Trp2
Type Biomolecule
Formula
Role loaded material
7

CpG ODN 1826

CpG ODN CpG
Type Biomolecule
Formula
Role loaded material

Properties

Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
B16F10 tumor bearing C57BL/6 mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

LCP-based p-Trp2 vaccine nanoparticles

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • p-Trp2 peptide
  • calcium(II) chloride
  • CpG ODN 1826
  1. Ia0qVe7KZpV
  2. 9CkMwGhV0pgBm
Product

LCP-based p-Trp2 vaccine nanoparticles

References

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