Loading ...

Fast insight into nanotechnology

Access easily searchable nanoscience data, synthesis methods and literature

sorafenib-loaded TPGS-PLGA nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

D-α-tocopheryl polyethylene glycol 1000 succinate

TPGS
Type Polymer
Formula
Role layer
3

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide

sorafenib SFN SOR SF
Type Single Compound
Formula C21H16ClF3N4O3
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

More information available to subscribers only.

Or, view sample content

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

More information available to subscribers only.

Or, view sample content

Characterization

Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

sorafenib-loaded TPGS-PLGA nanoparticles

Size: ~ 130 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • D-α-tocopheryl polyethylene glycol 1000 succinate
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  • poly(lactic-co-glycolic acid)
  1. QzTl
Product

sorafenib-loaded TPGS-PLGA nanoparticles

Size: ~ 175 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  • D-α-tocopheryl polyethylene glycol 1000 succinate
  • poly(lactic-co-glycolic acid)
  1. R3qs
Product

sorafenib-loaded TPGS-PLGA nanoparticles

Size: ~ 125 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • D-α-tocopheryl polyethylene glycol 1000 succinate
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  • poly(lactic-co-glycolic acid)
  1. 5Nps
Product

sorafenib-loaded TPGS-PLGA nanoparticles

Size: ~ 170 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • D-α-tocopheryl polyethylene glycol 1000 succinate
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  • poly(lactic-co-glycolic acid)
  1. JZne
Product

sorafenib-loaded TPGS-PLGA nanoparticles

Size: ~ 130 nm

Medium/Support: none

References

Full content is available to subscribers only

To view content please choose from the following:

We use cookies to improve your experience with our site. More information

Sign up for a free trial