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sorafenib-loaded TPGS-PLGA nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

D-α-tocopheryl polyethylene glycol 1000 succinate

TPGS
Type Polymer
Formula
Role layer
3

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide

sorafenib SFN SOR SF
Type Single Compound
Formula C21H16ClF3N4O3
Role loaded material

Properties

General physical and chemical properties

Property Value Source
Zeta potential

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Applications

Area Application Source
medicine/veterinary

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Characterization

Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

sorafenib-loaded TPGS-PLGA nanoparticles

Method 2

Type: Physical formation
Source:
Starting materials
  • D-α-tocopheryl polyethylene glycol 1000 succinate
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  • poly(lactic-co-glycolic acid)
  1. DtVG
Product

sorafenib-loaded TPGS-PLGA nanoparticles

Method 3

Type: Physical formation
Source:
Starting materials
  • D-α-tocopheryl polyethylene glycol 1000 succinate
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  • poly(lactic-co-glycolic acid)
  1. AIB7
Product

sorafenib-loaded TPGS-PLGA nanoparticles

Method 4

Type: Physical formation
Source:
Starting materials
  • D-α-tocopheryl polyethylene glycol 1000 succinate
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  • poly(lactic-co-glycolic acid)
  1. OhiO
Product

sorafenib-loaded TPGS-PLGA nanoparticles

Method 5

Type: Physical formation
Source:
Starting materials
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  • D-α-tocopheryl polyethylene glycol 1000 succinate
  • poly(lactic-co-glycolic acid)
  1. SOqF
Product

sorafenib-loaded TPGS-PLGA nanoparticles

References

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