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doxorubicin-loaded oligonucleotide-conjugated mesoporous silica nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

silicon dioxide

silicic oxide silica
Type Single Compound
Formula SiO2
Role core
2

(3-aminopropyl)trimethoxysilane moiety

(3-aminopropyl)trimethoxysilane moiety (3-aminopropyl)triethoxysilane moiety γ-aminopropyltriethoxy silane moiety 3-aminopropyltrimethoxysilane moiety γ-aminopropyltriethoxysilane moiety 3-aminopropyltriethoxysilane moiety (3-aminopropyl)trioxysilane moiety (3-aminopropyl)silanetrioxy group 3-aminopropylsilanetrioxy group 3-aminopropylsiloxy fragment 3-aminopropyl silane moiety 3-aminopropylsilane moiety γ-APTES moiety 3-APTS moiety APTES moiety APTMS moiety AMPS moiety APTS moiety APS moiety
Type Single Compound
Formula -C3H8NO3Si-
Role layer
3

4-[(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl]cyclohexane-1-carbonyl group

(succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate) moiety N-succinimidyl 4-(maleimidomethyl)cyclohexanecarboxylate unit succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate 4-(N-maleimidomethyl)cyclohexane-1-carboxylic acid moiety 4-(N-maleimidomethyl)cyclohexane-1-carboxylate moiety 4-(N-maleimidomethyl)cyclohexane-1-carbonyl moiety 4-(N-maleimidomethyl)cyclohexane-1-carbonyl group 4-(N-maleimidomethyl)cyclohexane-1-carbonyl Sulfo-SMCC moiety sulfo-SMCC moiety sulfo-SMCC unit SMCC moiety SMCC spacer SMCC unit
Type Single Compound
Formula -C12H14NO3
Role layer
4

5'-(6-mercaptohexyl)-modified d(TTATCGCTGATTCAA)

Type Biomolecule
Formula
Role layer
5

doxorubicin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
glutathione-induced drug release

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Applications

Characterization

Method Nanomaterial Variant Source
infrared spectroscopy

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Biological effects

Preparation

Method 1

Type: Physical formation
Source:
  1. k4Vhf1Kg
  2. vJrAqzPb
Product

doxorubicin-loaded oligonucleotide-conjugated mesoporous silica nanoparticles

Size: not specified

Medium/Support: none

References

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