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siRNA/doxorubicin-loaded GTC/PSS/TAT peptide-coated mesoporous silica nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

silicon dioxide

silicic oxide silica
Type Single Compound
Formula SiO2
Role core
2

3-aminopropyltriethoxysilane

APTES
Type Single Compound
Formula C9H23NO3Si
Role layer
3

N-acetylated TAT

TAT
Type Biomolecule
Formula
Role layer
4

poly(styrenesulfonate)

PSS
Type Polymer
Formula
Role layer
5

galactose-modified trimethyl chitosan-cysteine conjugate

GTC
Type Biomolecule
Formula
Role layer
6

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material
7

vascular endothelial growth factor siRNA

VEGF siRNA siVEGF
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release dependent on pH

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Applications

Area Application Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Source
QGY-7703 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

siRNA/doxorubicin-loaded GTC/PSS/TAT peptide-coated mesoporous silica nanoparticles

References

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