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EGCP1-DOX based nano drug vehicle

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(oligo(ethylene glycol) methacrylate-co-methacryloylhydrazine)

OEGMA:MAH copolymer EGCP1
Type Polymer
Formula
Role raw materials
2

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role graft

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female BALB/c nude mouse bearing BCap-37 breast cancer xenograft

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • doxorubicin hydrogen chloride
  • poly(oligo(ethylene glycol) methacrylate-co-methacryloylhydrazine)
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  2. M9EV
  3. M0CC4yQpdBVGjR4o8TlHEXrB
  4. BDmvTCFK
  5. orAVrxfeAkQ5vayj
  6. mzVcZbQ
  7. hf0S
Product

EGCP1-DOX based nano drug vehicle

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

EGCP1-DOX based nano drug vehicle

Hydrodynamic diameter: 189 nm

Medium: phosphate buffer solution

Support: none

Method 3

Type: Physical formation
Source:
Product

EGCP1-DOX based nano drug vehicle

Hydrodynamic diameter: ~ 204 - ~ 209 nm

Medium: Na2HPO4-citric acid solution

Support: none

Method 4

Type: Physical formation
Source:
Product

EGCP1-DOX based nano drug vehicle

Size: not specified

Medium: NaAc/AcOH buffer with NaCl

Support: none

Method 5

Type: Physical formation
Source:
  1. nbJZwX
Product

EGCP1-DOX based nano drug vehicle

Hydrodynamic diameter: ~ 199 - ~ 214 nm

Medium: NaCl-Na2HPO4-citric acid solution

Support: none

References

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