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GTC/PAH-Cit-coated doxorubicin-loaded TAT peptide-coated mesoporous silica nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

silicon dioxide

silicic oxide silica
Type Single Compound
Formula SiO2
Role core
2

3-aminopropyltriethoxysilane

APTES
Type Single Compound
Formula C9H23NO3Si
Role layer
3

N-acetylated TAT

TAT
Type Biomolecule
Formula
Role layer
4

poly(allylamine hydrochloride)-citraconic anhydride

PAH-Cit
Type Polymer
Formula
Role layer
5

galactose-modified trimethyl chitosan-cysteine conjugate

GTC
Type Biomolecule
Formula
Role layer
6

doxorubicin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
QGY-7703 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

GTC/PAH-Cit-coated doxorubicin-loaded TAT peptide-coated mesoporous silica nanoparticles

Hydrodynamic diameter: 51.4 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
  1. XIHTC
Product

GTC/PAH-Cit-coated doxorubicin-loaded TAT peptide-coated mesoporous silica nanoparticles

Size: not specified

Medium/Support: none

References

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