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methotrexate - loaded poly(lactic-co-glycolic acid) iron (Fe)/ gold (Au) half-shell nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

methotrexate

abitrexate folex MTX
Type Single Compound
Formula C20H22N8O5
Role loaded material
3

pluronic F-127

Type Polymer
Formula
Role partial layer
4

iron

Type Single Compound
Formula Fe
Role partial layer
5

gold

Type Single Compound
Formula Au
Role layer
6

SH-PEG-COOH

Type Polymer
Formula
Role layer

Properties

Applications

Characterization

Method Nanomaterial Variant Source
UV-Vis-NIR optical spectroscopy

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Biological effects

Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • pluronic F-127
  • poly(lactic-co-glycolic acid)
  • methotrexate
  1. aXN742MwfPUxmwSfXhuak0qLrZ9Bs89EKGS
  2. BOgVhqX6CZ0HlD2
Product

methotrexate - loaded poly(lactic-co-glycolic acid) iron (Fe)/ gold (Au) half-shell nanoparticles

Thickness: 10 nm

Thickness: 5 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • pluronic F-127
  • poly(lactic-co-glycolic acid)
  • methotrexate
  1. Oyep7MmEjElCLbSnsXTe8x11NMJHYOTKoVr
  2. vHd0LuO5o2DrS4d
Product

methotrexate - loaded poly(lactic-co-glycolic acid) iron (Fe)/ gold (Au) half-shell nanoparticles

Thickness: 10 nm

Medium: phosphate buffer solution

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • pluronic F-127
  • poly(lactic-co-glycolic acid)
  • methotrexate
  1. OWhIrxOZS4iuTDwJ7tkeGE7MANsxOdMrR3l
  2. UYfNkX4Mb8EBhlC
Product

methotrexate - loaded poly(lactic-co-glycolic acid) iron (Fe)/ gold (Au) half-shell nanoparticles

Thickness: 10 nm

Thickness: 15 nm

Medium: phosphate buffer solution

Support: none

References

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