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docetaxel-loaded oxidized single-wall carbon nanohorns modified with polyethylene glycol/anti-VEGF monoclonal antibody

Based on

1 Articles
2015 Most recent source

Composition

1

docetaxel-loaded oxidized single-wall carbon nanohorns

DTX@oxSWCNH
Type Nano Material
Formula
Role core
2

1,2-distearoyl-sn-glycero-3-phosphoethanolamine conjugated poly(ethylene glycol)

1,2-distearoyl-sn-glycero-3-phosphoethanolamine conjugated poly(ethylene oxide) DSPE-conjugated polyethylene glycol DSPE-conjugated polyethylene oxide DSPE-conjugated polyoxyethylene DSPE-conjugated PEO DSPE-conjugated POE DSPE-PEG-COOH
Type Polymer
Formula
Role layer
3

humanized anti-vascular endothelial growth factor antibody

anti-VEGF165 antibody
Type Biomolecule
Formula
Role layer
4

docetaxel

DTX TXT
Type Single Compound
Formula C43H53NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
human breast cancer stem cells (MCF-7)

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine conjugated poly(ethylene glycol)
  • humanized anti-vascular endothelial growth factor antibody
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  2. K4W2twGRPMQFqLbrzLXF2
  3. ctH
  4. NzFewU3
Product

docetaxel-loaded oxidized single-wall carbon nanohorns modified with polyethylene glycol/anti-VEGF monoclonal antibody

Size: 70 - 600 nm

Medium: phosphate buffer solution

Support: none

References

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