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doxorubicin-loaded fluorescent boronate nanoparticles in phosphate buffered saline

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

phenylboronic acid-modified poly(lactic acid)-poly(ethyleneimine) copolymer

Type Polymer
Formula
Role raw materials
2

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
MCF-7 human breast cancer cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • PLA-PEI-CPB copolymer
  • adriblastin
  • PLA-PEI-DHB copolymer
  1. 9JoGnVP5bRMC85KASBNB416aKGIcus9i
  2. 00Dz6ZQx5e
  3. 3jj6Kf8
  4. SeTYm51YZl9uAXiru5unbR1
Product

doxorubicin-loaded fluorescent boronate nanoparticles in phosphate buffered saline

Hydrodynamic diameter: 222.1 - 231.3 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • PLA-PEI-CPB copolymer
  • adriblastin
  • PLA-PEI-DHB copolymer
  1. VEnCrxDAsUHXOuSWKV7VOupVBKemvvmS
  2. AVeLUp2sQ6
  3. iF2jqbA
  4. R7rnIxOznMNmOBK6M8hzw9i
Product

doxorubicin-loaded fluorescent boronate nanoparticles in phosphate buffered saline

Hydrodynamic diameter: 236.3 - 241.9 nm

Medium: phosphate buffer solution

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • PLA-PEI-CPB copolymer
  • adriblastin
  • PLA-PEI-DHB copolymer
  1. XCzpCIVxk8dD4oajVQ6mvlX5ESAjWeil
  2. pFzRzXVFIv
  3. TMogvSu
  4. g5yx8L3l0HOjcvOYEhBoAqH
Product

doxorubicin-loaded fluorescent boronate nanoparticles in phosphate buffered saline

Size: not specified

Medium/Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • PLA-PEI-CPB copolymer
  • adriblastin
  • PLA-PEI-DHB copolymer
  1. zlV3YYenEfFw7ph99Z4KttrC1q6vG03l
  2. L0zOxDhpd4
  3. 4bNptpr
  4. wnJEtFq8ouBw1HznZxOC35F
Product

doxorubicin-loaded fluorescent boronate nanoparticles in phosphate buffered saline

Hydrodynamic diameter: 217.0 - 225.6 nm

Medium: phosphate buffer solution

Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • PLA-PEI-CPB copolymer
  • adriblastin
  • PLA-PEI-DHB copolymer
  1. Ha4lKIevlJyLVdfNgs1PL2SVxR2uKAks
  2. 2llkliqwUr
  3. K4DfnYX
  4. l80Ux0qAieRm2IiYtFrr5tI
Product

doxorubicin-loaded fluorescent boronate nanoparticles in phosphate buffered saline

Hydrodynamic diameter: 289.3 - 297.9 nm

Medium: phosphate buffer solution

Support: none

References

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