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paclitaxel/small interfering RNA loaded cystamine/octanedioic acid/branched polyethyleneimine-modified hyaluronic acid micelles

Based on

1 Articles
2015 Most recent source

Composition

1

octanedioic acid

azelaic acid suberic acid C8H14O4
Type Single Compound
Formula C8H14O4
Role core
2

Paclitaxel

Plaxicel Abraxane Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material
3

cystamine modified hyaluronic acid

Type Biomolecule
Formula
Role layer
4

branched poly(iminoethylene)

branched polyethyleneimine branched polyaziridine BPEI
Type Polymer
Formula
Role layer
5

small interfering RNA

siRNA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Source
increased release rate of paclitaxel in reducing environment dependent on glutathione concentration

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Applications

Characterization

Method Source
atomic force microscopy

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Biological effects

Biological system Test details Source
MDA-MB-231 cells

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Preparation

Method 1

Type: Physical formation
Source:
  1. a2Sc0Ldf1R5toFCk
Product

paclitaxel/small interfering RNA loaded cystamine/octanedioic acid/branched polyethyleneimine-modified hyaluronic acid micelles

Method 2

Type: Physical formation
Source:
  1. FOeheuFikVy8zstR
Product

paclitaxel/small interfering RNA loaded cystamine/octanedioic acid/branched polyethyleneimine-modified hyaluronic acid micelles

References

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