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MCNP-ATAP complexes

Based on

1 Articles
2014 Most recent source

Composition

1

PEI-coated magnetic nanoparticles

PEI-coated MNP
Type Nano Material
Formula
Role core
2

mercaptopropionic acid moiety

3-sulfanylpropanal moiety SPDP linker MPA moiety
Type Single Compound
Formula -C3H4OS-
Role layer
3

thiol-PEG moiety bearing tumor targeting peptide

thiol-PEG-CRGDK/RGPD/EC SH-PEG-iRGD
Type Biomolecule
Formula
Role partial layer
4

mitochondria-targeting pro-apoptotic amphipathic tail-anchoring peptide

Ac-KKFEPKSGWMTFLEVTGKIAEMLSLLKQYC-OH SH-ATAP
Type Biomolecule
Formula
Role partial layer

Properties

Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
high-resolution transmission electron microscopy

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Biological effects

Biological system Test details Source
brain tumor U87vIII cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • thiol-PEG moiety bearing tumor targeting peptide
  • mitochondria-targeting pro-apoptotic amphipathic tail-anchoring peptide
  • SPDP-linked MCNP-PEI complexes
  1. bePa80SYG
Product

MCNP-ATAP complexes

References

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