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vorinostat-encapsulated human serum albumin nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

human serum albumin

HSA
Type Biomolecule
Formula
Role raw materials
2

N-Hydroxy-N`-phenyloctanediamide

suberanilohydroxamic acid vorinostat ZolinzaTM SAHA
Type Single Compound
Formula C14H20N2O3
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
acute myeloid leukemia-diseased human-isolated peripheral blood/bone marrow derived mononuclear cell

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Preparation

Method 1

Type: Chemical synthesis
Source:
Product

vorinostat-encapsulated human serum albumin nanoparticles

Hydrodynamic diameter: ~ 77 - 105 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • human serum albumin
  • N-Hydroxy-N`-phenyloctanediamide
  • water
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Product

vorinostat-encapsulated human serum albumin nanoparticles

Hydrodynamic diameter: ~ 77 - 105 nm

Medium: water

Support: none

References

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