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AuNP-C225-gemcitabine-mPEG

Based on

1 Articles
2014 Most recent source

Composition

1

gold

Type Single Compound
Formula Au
Role core
2

(4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl) oxolan-2-yl]-1,2-dihydropyrimidin-2-one)

2',2'-difluoro-2'-deoxycytidine 2',2'-difluorodeoxycytidine gemcitabine gemzar dFdC GEM Gem
Type Single Compound
Formula C9H11F2N3O4
Role layer
3

SPT-0012 alkane monothiol linker-modified human-mouse chimeric monoclonal anti-epidermal growth factor receptor IgG1 antibody

SPT-0012 alkane monothiol linker-modified human-mouse chimeric monoclonal anti-EGFR IgG1 antibody SPT-0012 alkane monothiol linker-modified cetuximab SPT-0012 alkane monothiol linker-modified C225
Type Biomolecule
Formula
Role layer
4

mPEG-SH

Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
cetuximab dissociation

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BalbC/Nu mouse carrying dorsal subcutaneous implantation of human hepatocellular carcinoma Hep3B cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

AuNP-C225-gemcitabine-mPEG

Hydrodynamic diameter: 68 nm

Medium: water

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
Product

AuNP-C225-gemcitabine-mPEG

Size: not specified

Medium/Support: none

References

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