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nucleic acid-based polymeric nanoparticles

Based on

1 Articles
1 Patents
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

small molecule DNA

Type Biomolecule
Formula
Role raw materials
2

tetrakis(4-triazolebutylphenyl)methane moiety

Type Single Compound
Formula -C49H52N12-
Role framework element

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Product

nucleic acid-based polymeric nanoparticles

Diameter: ~ 170 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • complementary small molecule-DNA hybrid
  • small molecule DNA hybrid
  • Tris-buffered saline
Product

nucleic acid-based polymeric nanoparticles

Diameter: 17 - 25 nm

Hydrodynamic diameter: 18 - 30 nm

Medium: Tris-buffered saline

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • complementary small molecule-DNA hybrid
  • small molecule DNA hybrid
  • Tris-buffered saline
Product

nucleic acid-based polymeric nanoparticles

Diameter: ~ 170 nm

Hydrodynamic diameter: ~ 220 nm

Medium: Tris-buffered saline

Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • complementary small molecule-DNA hybrid
  • small molecule DNA hybrid
  • Tris-buffered saline
  1. wNCIP5n
Product

nucleic acid-based polymeric nanoparticles

Diameter: ~ 20 - ~ 40 nm

Hydrodynamic diameter: ~ 26 nm

Medium: Tris-buffered saline

Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • complementary small molecule-DNA hybrid
  • small molecule DNA hybrid
  • Tris-buffered saline
  1. W6zqzNUsZ4n
Product

nucleic acid-based polymeric nanoparticles

Hydrodynamic diameter: ~ 240 nm

Medium: Tris-buffered saline

Support: none

References

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