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EGRF antibody-conjugated PLGA-Casein core/shell nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

Paclitaxel

Plaxicel Abraxane Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material
3

casein

Type Biomolecule
Formula
Role layer
4

(-)-epigallocatechin-3-O-gallate

(-)-epigallocatechin-3-gallate (-)-epigallocatechin gallate epigallocatechin-3-O-gallate epigallocatechin-3-gallate epigallocatechin gallate EGCG EGCg
Type Single Compound
Formula C22H18O11
Role loaded material
5

anti-epithelial growth factor receptor antibody

epithelial growth factor receptor antibody anti-EGFR antibody EGFR antibody
Type Biomolecule
Formula
Role layer

Properties

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
cancer patient derived tumor tissue overexpressing epidermal growth factor receptor (EGRF)

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Preparation

Method 1

Type: Physical formation
Source:
Product

EGRF antibody-conjugated PLGA-Casein core/shell nanoparticles

Hydrodynamic diameter: 207 - 353 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
Product

EGRF antibody-conjugated PLGA-Casein core/shell nanoparticles

Size: not specified

Medium: cell culture medium

Support: none

Method 3

Type: Chemical synthesis
Source:
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  2. SsGnBZCkrcD2KQHh0KEXroZf2PLJasGK7t2hZVB01Fiixy
  3. ycev4U4ZleW8qF6gvbiP
  4. UZrN
Product

EGRF antibody-conjugated PLGA-Casein core/shell nanoparticles

Diameter: 203 - 297 nm

Medium/Support: none

References

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