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mannosylated polymer nanoparticle-siRNA complex

Based on

1 Articles
2015 Most recent source

Composition

1

polymer

Type Polymer
Formula
Role core
2

poly(2-(N,N-dimethylamino) ethyl methacrylate)

PDMAEMA
Type Polymer
Formula
Role layer
3

FAM-labeled silencing RNA

Type Biomolecule
Formula
Role loaded material
4

poly(2-azidoethyl methacrylate)

PAzEMA
Type Polymer
Formula
Role layer
5

mixture of substance based on (D-mannose)

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
genetic engineering

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
enriched tumor associated macrophages (TAM) population from mouse murine mammary tumor

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • n-butyl methacrylate
  • 2-(N,N-dimethylamino) ethyl methacrylate
  • 2-n-propylacrylic acid
Product

mannosylated polymer nanoparticle-siRNA complex

Size: not specified

Medium: water

Support: none

References

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