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hybrid lipid-polymer nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

water

Type Single Compound
Formula H2O
Role core
2

siRNA

Type Biomolecule
Formula
Role loaded material
3

PAMAM G0-C14

G0-C14
Type Single Compound
Formula C103H210N10O10
Role layer
4

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role layer
5

soybean lecithin

Type Complex Compound
Formula
Role layer
6

1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) 2000

DSPE-PEG 2000 DSPE-PEG
Type Polymer
Formula
Role layer

Properties

Applications

Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
luciferase-expressing human epitheloid cervix carcinoma (Luc-HeLa) cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • luciferase small interfering RNA
  • PAMAM G0-C14
  • poly(lactic-co-glycolic acid)
  1. rnl6EENt8YvCzcswBNDJCccxvQ
  2. 7kU6OclsrFJAwVyv
Product

hybrid lipid-polymer nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • PAMAM G0-C14
  • poly(lactic-co-glycolic acid)
  • siRNA
  1. ggX1rAJz5A7tHiR0tHyFUs9jqh
  2. UgLNDumCDQ9ZmVPR
Product

hybrid lipid-polymer nanoparticles

Size: not specified

Medium/Support: none

References

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