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hybrid lipid-polymer nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

1

water

Type Single Compound
Formula H2O
Role core
2

luciferase small interfering RNA

luciferase siRNA
Type Biomolecule
Formula
Role loaded material
3

PAMAM G0-C14

G0-C14
Type Single Compound
Formula C103H210N10O10
Role layer
4

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role layer
5

soybean lecithin

Type Complex Compound
Formula
Role layer
6

1,2-distearoyl-sn-glycero-3-phosphatidylethanolamine-poly(ethylene glycol) 2000

DSPE-PEG 2000 DSPE-PEG
Type Polymer
Formula
Role layer

Properties

Applications

Characterization

Method Source
transmission electron microscopy

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Biological effects

Biological system Test details Source
luciferase-expressing human epitheloid cervix carcinoma (Luc-HeLa) cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • luciferase small interfering RNA
  • PAMAM G0-C14
  • poly(lactic-co-glycolic acid)
  1. mLbQMdPJ1o8w9v6afF9Pc7YeM5
  2. rKzMqZ1iITV5ju8H
Product

hybrid lipid-polymer nanoparticles

Method 2

Type: Physical formation
Source:
Starting materials
  • PAMAM G0-C14
  • poly(lactic-co-glycolic acid)
  • siRNA
  1. OIhmG0TBjyo51PlrRHqoZufa4l
  2. s0CxgZEAP9JvlUBt
Product

hybrid lipid-polymer nanoparticles

References

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