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coumarin 6-loaded carbosilane cationic dendrons of second generation-functionalized poly-(lactic-co-glycolic) acid nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

carbosilane cationic dendrons of second generation

dendron G2SN
Type Complex Compound
Formula
Role layer
3

3-(1,3-benzothiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one

3-(2-benzothiazolyl)-N,N-diethylumbelliferylamine 3-(2-benzothiazolyl)-7-(diethylamino)coumarin 6-coumarin coumarin 6 coumarin-6 C6 dye Cou6 C-6
Type Single Compound
Formula C20H18N2O2S
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human blood

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • 3-(1,3-benzothiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one
  • poly(lactic-co-glycolic acid)
  1. W7SABCHhU7ejV
  2. fUBj18uH9lDxHrulRCuPVZrtc
  3. Ijypa8DRTfFngJCkqrxw7iUixYrr
Product

coumarin 6-loaded carbosilane cationic dendrons of second generation-functionalized poly-(lactic-co-glycolic) acid nanoparticles

Hydrodynamic radius: 20 - 34 nm

Medium: veronal buffered saline

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • 3-(1,3-benzothiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one
  • poly(lactic-co-glycolic acid)
  1. jCn42cfeSd6ia
  2. YvNtk12kAY1slCYKy7gnmps0y
  3. qZJe2ywmy1ro91Q8QlBVOBuj6d1p
Product

coumarin 6-loaded carbosilane cationic dendrons of second generation-functionalized poly-(lactic-co-glycolic) acid nanoparticles

Hydrodynamic radius: 23 - 25 nm

Medium: phosphate buffer solution

Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • 3-(1,3-benzothiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one
  • poly(lactic-co-glycolic acid)
  1. 39VlZf5HQVRrk
  2. srJ35JHIDAKDNwg67mrJhX2Sh
  3. coO7WtrMjokVZI2yZ58ut3SHzGPo
Product

coumarin 6-loaded carbosilane cationic dendrons of second generation-functionalized poly-(lactic-co-glycolic) acid nanoparticles

Size: not specified

Medium: veronal buffered saline/human serum albumin

Support: none

References

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