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CpG oligonucleotide-functionalized super paramagnetic iron oxide nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

iron(II,III) oxide

magnetite
Type Single Compound
Formula Fe3O4
Role core
2

silane and thiol-modified PEG

Type Polymer
Formula
Role layer
3

phosphorothioated CpG oligonucleotide

CpG oligonucleotide
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
N9 mouse microglia cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • dithiothreitol
  • phosphorothioated CpG oligonucleotide with terminal dithiol
  1. maszv0ENIGyXqS9x
  2. J0CIlhTJ
Product

CpG oligonucleotide-functionalized super paramagnetic iron oxide nanoparticles

Hydrodynamic diameter: 89 - 99 nm

Size: ~ 30 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
  1. oo9WbzF2hzGXicaenv
Product

CpG oligonucleotide-functionalized super paramagnetic iron oxide nanoparticles

Size: ~ 30 nm

Medium/Support: none

References

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