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doxorubicin hydrochloride-loaded dual stimuli polysaccharide nanovesicles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

phosphate buffer solution

PBS
Type Complex Compound
Formula
Role core
2

doxorubicin hydrogen chloride

adriblastin hydrochloride doxorubicin hydrochloride adriamycin hydrochloride doxorubicin hydrochoride adriblastin HCl salt adriamycin HCl salt DOX hydrochloride DXR hydrochloride doxorubicin HCl DOX*HCl DOX-HCl DOX·HCl DXR HCl DXR*HCl Dox HCl Dox*HCl DOXS
Type Single Compound
Formula C27H29NO11*HCl
Role loaded material
3

amine-functionalized 3-pentadecylphenol-modified dextran

PDP amine-modified dextran DEX-IM-PDP DEX-IM
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on esterase or serum presence

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
breast cancer MCF-7 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • amine-functionalized 3-pentadecylphenol-modified dextran
  • water soluble intercalating doxorubicin hydrochloride
  1. 2sHZl9bFRSdO7cK5
  2. gQkKWttt
Product

doxorubicin hydrochloride-loaded dual stimuli polysaccharide nanovesicles

Diameter: 195 - 220 nm

Thickness: 10 - 16 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

doxorubicin hydrochloride-loaded dual stimuli polysaccharide nanovesicles

Hydrodynamic diameter: 230 nm

Medium: phosphate buffer solution

Support: none

References

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