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doxorubicin-encapsulated Pluronic F127-chitosan nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

doxorubicin hydrochloride

Dox HCl Dox*HCl
Type Single Compound
Formula C27H30ClNO11
Role core
2

Pluronic F127-modified chitosan

Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human breast cancer MCF-7 cells overexpressing CD44<sup>+</sup>, CD133<sup>+</sup> and CD44<sup>+</sup>CD133<sup>+</sup> receptors

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. D1I0jrznRUOpzgBP
  2. ePoYOH0
Product

doxorubicin-encapsulated Pluronic F127-chitosan nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  1. 4sWzA
Product

doxorubicin-encapsulated Pluronic F127-chitosan nanoparticles

Hydrodynamic diameter: 21.4 - 279.6 nm

Medium: sodium potassium solution

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  1. J8g0j
Product

doxorubicin-encapsulated Pluronic F127-chitosan nanoparticles

Hydrodynamic diameter: 21.4 - 279.6 nm

Medium: sodium potassium solution

Support: none

References

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