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nanoscale self-titrating activatable therapeutic

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

Vacuous

Type
Formula
Role core
2

heparin

Type Biomolecule
Formula
Role layer
3

cationic peptide

Type Biomolecule
Formula
Role layer
4

poly(ethylene glycol)-succinimidyl valerate moiety

PEG-SVA moiety
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Source
effective heparin activity

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Applications

Area Application Source
drug delivery

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
healthy female Swiss Webster mice

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • poly(ethylene glycol)-succinimidyl valerate
  • cationic peptide
  1. pg4qQMH37lqgty93
Product

nanoscale self-titrating activatable therapeutic

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • poly(ethylene glycol)-succinimidyl valerate
  • cationic peptide
  1. BAEmhKCxT7c3UoBg
Product

nanoscale self-titrating activatable therapeutic

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • poly(ethylene glycol)-succinimidyl valerate
  • cationic peptide
  1. 2PH08ca42YuDS32Y
Product

nanoscale self-titrating activatable therapeutic

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • poly(ethylene glycol)-succinimidyl valerate
  • cationic peptide
  1. 8KD352K0ACMjK4Cn
Product

nanoscale self-titrating activatable therapeutic

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • poly(ethylene glycol)-succinimidyl valerate
  • cationic peptide
  1. HABOhkLda8ww3NI8
Product

nanoscale self-titrating activatable therapeutic

References

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