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camptothecin-loaded PEG-P(Lys(DP)) micelles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

PEG-P(Lys(DP))

Type Polymer
Formula
Role raw materials
2

(S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione

1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione (S)-(+)-camptothecin camptothecin CPT CMT CP
Type Single Compound
Formula C20H16N2O4
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
balb/c nu/nu mice with subcutaneous AY27 xenografts

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • PEG-P(Lys(DP))
  • (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
  1. Fo53Uc77DfPhY0UfKw81s2Iix1VtRkos3iJclz6dcNw1xvMUf0Q9f
  2. dm9kn3HYCNw27NRosJlKOu0SnrZqEa
  3. iW8
  4. RjRCBi2wsb
  5. hWLV
Product

camptothecin-loaded PEG-P(Lys(DP)) micelles

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • PEG-P(Lys(DP))
  • (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
  1. iVwhyqaQGP3qTrpHRCiUhEZMTNo4YRRmd0jZexgkA38CFrE2OUV5G
  2. nYakzGA9arPAlVcpgybuhLr4h3YOrw
  3. 2cm
  4. twxjuuch3a
  5. Y3jU
Product

camptothecin-loaded PEG-P(Lys(DP)) micelles

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • PEG-P(Lys(DP))
  • (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
  1. 9iLZh7ASaP2OGhlpVPVYfNUfzygamEN9F3ytlyv9HNINvlxvjZ6UV
  2. KeCZIEiX65eDP0MbEfiyKgQJDN6n96
  3. 5kr
  4. soUvS3kXRN
  5. 8IJH
Product

camptothecin-loaded PEG-P(Lys(DP)) micelles

References

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