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RSC/hyaluronic acid

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

siRNA/dual-functionalized cationic liposome complex

RSC
Type Nano Material
Formula
Role core
2

hyaluronic acid

HA
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
electrophoretic mobility shift dependent on N:P (nitrogen in RSN<sub>3</sub>-L to phosphate in siRNA molar ratio)

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
A549 human lung adenocarcinoma epithelial cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • [(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
  • ditetradecyl 2-(4-(2-(2-(2-(2-(2,6-diaminohexanamido)-3-(1H-imidazol-4-yl) propanamido)ethyl)disulfanyl)ethylamino)-4-oxobutanamido)pentanedioate
  • azide-modified cholesterol
  1. S7Giem6t4wlQF7YtzAsWtyEdDE85Bp5m
Product

RSC/hyaluronic acid

Hydrodynamic diameter: ~ 240 nm

Medium: water

Support: none

References

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