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siRNA/dual-functionalized cationic liposome complex

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

water

Type Single Compound
Formula H2O
Role core
2

cpusiRNA2

Type Biomolecule
Formula
Role loaded material
3

lipid-polymer

SPC/LHSSG2C14
Type Complex Compound
Formula
Role layer
4

azide-modified cholesterol

Chol-N3
Type Single Compound
Formula C37H60N4O3
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
electrophoretic mobility shift dependent on N:P (nitrogen in RSN<sub>3</sub>-L to phosphate in siRNA molar ratio)

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
A549 human lung adenocarcinoma epithelial cells

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Preparation

Method 1

Type: Physical formation
Source:
  1. 6S0hWtQNQftNJgT8gP70XHvXd9EabUQ57erGxsnnVvlCsDqH4StqzqAwdWNQsxD
  2. wBgyLJ5zEHrW5ONV
  3. j9O5NF
Product

siRNA/dual-functionalized cationic liposome complex

Hydrodynamic diameter: 117 nm

Medium: water

Support: none

References

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