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5'-NH2-TTT TTC TCC ATG GTG CTC AC-Cy3-3' oligonucleotide-camptothecin conjugate nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

5'-NH2-TTT TTC TCC ATG GTG CTC AC-Cy3-3' oligonucleotide-camptothecin conjugate

DNA20-CPT conjugate
Type Complex Compound
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Source
critical micelle concentration

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
breast cancer SK-BR-3 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

5'-NH2-TTT TTC TCC ATG GTG CTC AC-Cy3-3' oligonucleotide-camptothecin conjugate nanoparticles

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • triphosgene
  • (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
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  2. pubnsi7o9BC68ofDyrThMINiumk
Product

5'-NH2-TTT TTC TCC ATG GTG CTC AC-Cy3-3' oligonucleotide-camptothecin conjugate nanoparticles

Method 3

Type: Chemical synthesis
Source:
Product

5'-NH2-TTT TTC TCC ATG GTG CTC AC-Cy3-3' oligonucleotide-camptothecin conjugate nanoparticles

References

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