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PEGylated G-quadruplex DNA aptamer-loaded gold nanostars

Based on

1 Articles
2015 Most recent source

Composition

1

gold

Type Single Compound
Formula Au
Role core
2

G-quadruplex DNA aptamer

AS1411 aptamer
Type Biomolecule
Formula
Role layer
3

thiolated polyethylene glycol

thiol-PEG
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
surface plasmon resonance

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
Crl:NU-Foxn1nu female nude mouse bearing fibrosarcoma

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  1. 8JtMOEf
Product

PEGylated G-quadruplex DNA aptamer-loaded gold nanostars

Hydrodynamic diameter: 64.9 - 71.9 nm

Tip-to-tip distance: ~ 50 nm

Medium: water

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  1. 4rePemS
Product

PEGylated G-quadruplex DNA aptamer-loaded gold nanostars

Tip-to-tip distance: ~ 50 nm

Medium: phosphate buffer solution

Support: none

References

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