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anti-HER2/neu antibody-conjugated 2,3-dimercaptosuccinic acid-coated iron/manganese ferrite core/shell nanoparticles

Based on

1 Patents
2011 Most recent source

Composition

1

iron

Type Single Compound
Formula Fe
Role core
2

manganese(II) ferrite

manganese iron oxide manganese ferrite Mn ferrite jacobsite MnFe2O4 MFO
Type Single Compound
Formula MnFe2O4
Role layer
3

meso-2,3-dimercaptosuccinic acid

2,3-dimercaptosuccinic acid dimercaptosuccinic acid DMSA
Type Single Compound
Formula C4H6O4S2
Role layer
4

(sulfosuccinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate)

sulfosuccinimidyl 4-(N-maleimidomethyl)-cyclohexane-1-carboxylate sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate sulfosuccinimidyl 4-(N-malemidomethyl)cyclohexane-1-carboxylate sulfosuccinimidyl 4-N-maleimidomethylcyclohexane-1-carboxylate sulfo-SMCC
Type Single Compound
Formula C16H18N2O9S
Role layer
5

anti-HER2/neu

herceptin
Type Biomolecule
Formula
Role layer

Properties

Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human SkBr3 breast cancer cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • (sulfosuccinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate)
  • anti-HER2/neu
  1. 8QKvjCg0y7rFaOxjJD4olVeS4
  2. fqv8Ef9JfyrYrq4C3S2el
Product

anti-HER2/neu antibody-conjugated 2,3-dimercaptosuccinic acid-coated iron/manganese ferrite core/shell nanoparticles

Diameter: ~ 16 nm

Medium/Support: none

References

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