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Paclitaxel-loaded methoxy-poly(ethylene glycol)-b-(N-(2-benzoyloxypropyl)methacrylamide) micelles

Based on

16 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly (lactic-co-glycolic acid)-g-dextran micelles

Dex-PLGA micelles
Type Nano Material
Formula
Role carriers
2

Paclitaxel

Abraxane Plaxicel Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Zeta potential

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
athymic male BALB/c nude mouse bearing human colonic carcinoma HCT-8/T tumor xenograft

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • amphiphilic biodegradable photoluminescent polymer
  1. 1jdmloOT0tWs6D
  2. KsP
Product

Paclitaxel-loaded methoxy-poly(ethylene glycol)-b-(N-(2-benzoyloxypropyl)methacrylamide) micelles

Size: not specified

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • PEG-PDHA
  • DMA-PEI-PDHA
  • Paclitaxel
  1. jnliu
  2. OUfz
Product

Paclitaxel-loaded methoxy-poly(ethylene glycol)-b-(N-(2-benzoyloxypropyl)methacrylamide) micelles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • amphiphilic biodegradable photoluminescent polymer
  1. na1we6JTAIjC61
  2. qI5
Product

Paclitaxel-loaded methoxy-poly(ethylene glycol)-b-(N-(2-benzoyloxypropyl)methacrylamide) micelles

Size: not specified

Medium: water

Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • PEG5k-CA8 telodendrimer
  • PEG5k-Cys4-L8-CA8 telodendrimer
  • Paclitaxel
  1. 4BsrPpAtlj
Product

Paclitaxel-loaded methoxy-poly(ethylene glycol)-b-(N-(2-benzoyloxypropyl)methacrylamide) micelles

Hydrodynamic diameter: 21 - 29 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • methoxy-poly(ethylene glycol)-b-(N-(2-benzoyloxypropyl)methacrylamide) solution in THF
  • water
  • Paclitaxel
  1. TZSJf8RD0AeIoAtgE1OMCaIV3
Product

Paclitaxel-loaded methoxy-poly(ethylene glycol)-b-(N-(2-benzoyloxypropyl)methacrylamide) micelles

Size: ~ 97 nm

Medium: water

Support: none

References

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