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Paclitaxel-loaded methoxy-poly(ethylene glycol)-b-(N-(2-benzoyloxypropyl)methacrylamide) micelles

Based on

17 Articles
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

PUR C-BC2000 nanoparticles

PUR C-BC2000 nanoparticles C-BC2000 NP MPEG-PLA
Type Nano Material
Formula
Role carriers
2

Paclitaxel

Plaxicel Abraxane Paxene Taxol PCL PAC PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Zeta potential

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
athymic male BALB/c nude mouse bearing human colonic carcinoma HCT-8/T tumor xenograft

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • PEG-PDHA
  • Paclitaxel
  1. VxnID
  2. RksL
Product

Paclitaxel-loaded methoxy-poly(ethylene glycol)-b-(N-(2-benzoyloxypropyl)methacrylamide) micelles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • PEG-PDHA
  • SA-PEI-PDHA
  • Paclitaxel
  1. 8tZr3
  2. xEWF
Product

Paclitaxel-loaded methoxy-poly(ethylene glycol)-b-(N-(2-benzoyloxypropyl)methacrylamide) micelles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • PEG-PDHA
  • DMA-PEI-PDHA
  • Paclitaxel
  1. rAY7R
  2. VDU7
Product

Paclitaxel-loaded methoxy-poly(ethylene glycol)-b-(N-(2-benzoyloxypropyl)methacrylamide) micelles

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • maleimide-polyethylene glycol-poly(lactide)
  • methoxy-polyethylene glycol-poly(lactide)
  • Paclitaxel
  1. JucXqQqoSjF8TlsKdUjz4Q6vfxC8Z5
Product

Paclitaxel-loaded methoxy-poly(ethylene glycol)-b-(N-(2-benzoyloxypropyl)methacrylamide) micelles

Diameter: 65.8 - 126.2 nm

Hydrodynamic diameter: 111.3 - 201.3 nm

Medium/Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • Paclitaxel
  • bPEG-SS-P123-PEI
  1. k6ygYs9wWjNvy8GwNYokVrbkNay
Product

Paclitaxel-loaded methoxy-poly(ethylene glycol)-b-(N-(2-benzoyloxypropyl)methacrylamide) micelles

Hydrodynamic diameter: ~ 150 nm

Interlayer spacing: 11.13 nm

Medium/Support: none

References

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