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Alexa-Fluor 647-tagged GFP siRNA-loaded PG1.C15/cholesterol/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

C15 epoxide-modified poly(amido amine) dendrimer generation 1

C15 epoxide-modified PAMAM dendrimer G1 PG1.C15
Type Complex Compound
Formula
Role core
2

small interfering ribonucleic acid

Kras siRNA
Type Biomolecule
Formula
Role loaded material
3

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000
Type Polymer
Formula
Role layer
4

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material

Properties

Applications

Area Application Source
drug delivery

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Characterization

Method Source
transmission electron microscopy

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Biological effects

Biological system Test details Source
female C57BL/6 mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • small interfering ribonucleic acid
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
See all (4)
  1. vncjTlI5vbARuN8M7uRq0XfOCN
Product

Alexa-Fluor 647-tagged GFP siRNA-loaded PG1.C15/cholesterol/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Method 2

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • small interfering ribonucleic acid
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
See all (4)
  1. nEseeWkALOteU2QNRdGGgNGNoW
Product

Alexa-Fluor 647-tagged GFP siRNA-loaded PG1.C15/cholesterol/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Method 3

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • small interfering ribonucleic acid
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
See all (4)
  1. e8CZveIJrSHp28PFRxSzHlTBHA
Product

Alexa-Fluor 647-tagged GFP siRNA-loaded PG1.C15/cholesterol/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Method 4

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • small interfering ribonucleic acid
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
See all (4)
  1. PS6HT7cqq85IeVm8XB9avbcrqI
Product

Alexa-Fluor 647-tagged GFP siRNA-loaded PG1.C15/cholesterol/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Method 5

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • small interfering ribonucleic acid
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
See all (4)
  1. elVTc7Ff1s13QKiJQ8grMfLo5t
Product

Alexa-Fluor 647-tagged GFP siRNA-loaded PG1.C15/cholesterol/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

References

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