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barbituric acid-loaded liposome-based mucus-penetrating particles

Based on

1 Articles
2015 Most recent source

Composition

1

water

Type Single Compound
Formula H2O
Role core
2

barbituric acid

BA
Type Single Compound
Formula C4H4N2O3
Role loaded material
3

1,2-distearoyl-sn-glycerophosphoethanolamine poly(ethylene glycol)2000/rhodamine-labeled 18:1 PE

DSPC/cholesterol/DSPE-PEG2k/rhodamine-labeled 18:1 PE lipid mixture
Type Complex Compound
Formula
Role layer

Properties

Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
CF-1 mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • [(2R)-2,3-di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
  • 1,2-distearoyl-sn-glycerophosphoethanolamine poly(ethylene glycol)2000
See all (4)
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  2. hIuwPo
  3. hQKjMnLOK2xVfY5l
Product

barbituric acid-loaded liposome-based mucus-penetrating particles

Hydrodynamic diameter: 119 - 133 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • [(2R)-2,3-di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
  • cholesterol
  • 1,2-distearoyl-sn-glycerophosphoethanolamine poly(ethylene glycol)2000
See all (4)
  1. qPZXTdjfOjAKVSS3shRHXJ
  2. HFD5gg
  3. GPEDtQQvfwbpFsL7
Product

barbituric acid-loaded liposome-based mucus-penetrating particles

Hydrodynamic diameter: 127 - 133 nm

Medium: phosphate buffer solution

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • [(2R)-2,3-di(octadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
  • 1,2-distearoyl-sn-glycerophosphoethanolamine poly(ethylene glycol)2000
See all (4)
  1. 2rGFsXbD4rPrKvI6Oxbqz8
  2. BLuERx
  3. 9YQwtzKmLgfaPsGY
Product

barbituric acid-loaded liposome-based mucus-penetrating particles

Hydrodynamic diameter: 125 - 135 nm

Medium: phosphate buffer solution

Support: none

References

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