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antisense-miR-21 and 10b loaded poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)-scrb-uPA peptide nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)-uPA-peptide conjugate mixture

PLGA-b-PEG-uPA mixture
Type Complex Compound
Formula
Role carriers
2

anti-miR-21 miRNA

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
TNBC xenograft mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)-scramble-peptide conjugate
  • anti-miR-10b miRNA
  • poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)-uPA-peptide conjugate
See all (5)
  1. sXcxKgb9Hsvx8xG
  2. AXI8P91
  3. F7pWFxGApH
Product

antisense-miR-21 and 10b loaded poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)-scrb-uPA peptide nanoparticles

Size: 142.8 - 154.8 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • anti-miR-10b miRNA
  • poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)-uPA-peptide conjugate
  • poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)
See all (4)
  1. T973mMbCLjaVRGQ
  2. ejmK2K1
  3. J3vMu2OfZ0
Product

antisense-miR-21 and 10b loaded poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)-scrb-uPA peptide nanoparticles

Size: 136.9 - 146.9 nm

Medium/Support: none

Method 3

Type: Physical formation
Source:
Product

antisense-miR-21 and 10b loaded poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)-scrb-uPA peptide nanoparticles

Size: 136.9 - 146.9 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)-uPA-peptide conjugate
  • poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)
  • anti-miR-21 miRNA
  1. MNiDhxraaNkndgd
  2. RDGGvl8
  3. JDDDrfvwDw
Product

antisense-miR-21 and 10b loaded poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)-scrb-uPA peptide nanoparticles

Size: 124 - 160 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
Product

antisense-miR-21 and 10b loaded poly(lactic-co-glycolic acid)-b-poly(ethylene glycol)-scrb-uPA peptide nanoparticles

Size: 142.8 - 154.8 nm

Medium: water

Support: none

References

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